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The Wednesday news update: January 21, 2009 1 Citation The Wednesday news update: January 21, 2009 Posted on January 21, 2009 by E. Michael D. ("Mike") Scott Today?s news includes information on: The use of markers for prognosis following first-line treatment for localized prostate cancer Results of a Phase II trial of neoadjuvant docetaxel + gefitinib prior to radical prostatectomy Results of a Phase III trial of gabapentin in management of ADT-related ?hot flashes?, technorati.com
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Iressa Proves Just As Effective As Chemotherapy For Lung Cancer 1 Citation Iressa Proves Just As Effective As Chemotherapy For Lung Cancer ScienceDaily Sun, 12/07/2008 - 20:00 Gefitinib, also known as Iressa, the once-promising targeted therapy for the treatment of nonsmall cell lung cancer, has proven as effective as chemotherapy as a second-line therapy for the disease with far fewer side effects, according to an international Phase III clinical trial., technorati.com
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Iressa as Good as Chemotherapy for Lung Cancer 1 Citation Iressa as Good as Chemotherapy for Lung Cancer Posted: November 24th, 2008 | Author: DylanRichards | Filed under: Health & Living | Tags: Cancer Researchers, Chemotherapy, Eight Months, Gefitinib, Healthday, Iressa, Lung Cancer, survival, technorati.com
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Searching for the Right Lung Cancer Treatment 1 Citation Lester Lee asked: Lung cancer is one of the most common forms of cancer. If you have been diagnosed with lung cancer, the next thing you should do is to discuss with your doctors the most suitable lung cancer treatment for you. There are various options available for the treatment of lung cancer, but you will need to discus&#, technorati.com
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European Researchers Find Estrogen Receptor Gene Amplification Occurs Rarely in Ovarian Cancer 1 Citation ?? ESR1 amplification is an uncommon mechanism for estrogen receptor overexpression in ovarian cancer occurring in about 2.1% of the total number of ovarian cancers. In general, this frequency parallels the fraction of ovarian cancers reported to show complete response to antiestrogenic therapies. Given the strong predictive power of ESR1 amplification for response to tamoxifen in breast cancer, an evaluation of such treatments in ESR1 amplified ovarian cance, technorati.com
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AstraZeneca?s Iressa receives EU positive opinion in NSCLC 1 Citation AstraZeneca announced Thursday that a committee of the European Medicines Agency recommended approval for Iressa (gefitinib) in adults with locally advanced or metastatic non-small-cell lung cancer (NSCLC) with activating mutations of EGFR-TK. The positive opinion stipulates, however, that the drugmaker must conduct a study to generate further data in a Caucasian population of patients with NSCLC. The drugmaker said it is in talks with the Committee for Medicinal Products for Human Use to fi, technorati.com
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Individuato il gene Happyhour, quello che porta all?alcolismo 1 Citation Una classe di farmaci già approvati come terapie contro il cancro potrebbe anche contribuire a sconfiggere la dipendenza dall?alcool . Questa è la conclusione di una scoperta sul gene delle mosche, soprannominato non a caso Happyhour , che ha un importante ruolo nel controllare la risposta degli insetti all?alcool. Negli animali una versione del gene mutata cresce sempre più resistente agli effetti sedativi dell?alcool . I ricercatori indicano un?ulteriore prova del fatto che il gene funz, technorati.com
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Prostate cancer news reports: Saturday, May 23, 2009 1 Citation Today?s news reports focus on four items:Development of aggressive prostate cancer from a single cell and tumorProstate size and risk for positive surgical marginsQuality of urinary function after different types of surgeryGefitinib as a single agent in treatment of CRPCLiu et al. have shown that aggressive prostate cancers develop from a single cancer cell and the resulting tumor, and that even if a man has multiple foci of cancer in his prostate in the beginning, it is just one of those foci t, technorati.com
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Roche to begin Phase III Tarceva study as initial therapy for NSCLC with EGFR mutations 1 Citation Roche announced that the company will commence a late-stage trial investigating whether Tarceva (erlotinib) is superior to chemotherapy as a first-line treatment in patients with non-small-cell lung cancer (NSCLC) who have genetic mutations in their epidermal growth factor receptor (EGFR). News of the upcoming study comes after AstraZeneca said an EU committee adopted a positive opinion for Iressa (gefitinib) in adults with NSCLC with the same gene mutation. Commenting on the potential compe, technorati.com
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AstraZeneca?s Iressa receives EU approval for lung cancer 1 Citation AstraZeneca announced Wednesday that the European Commission approved its oral drug Iressa (gefitinib) for the treatment of adults with locally advanced or metastatic non-small-cell lung cancer with activating mutations of EGFR-TK, across all lines of therapy. The company?s executive vice-president for development, Anders Ekblom, remarked that the approval will give patients with EGFR mutation positive tumours ?a more effective and better tolerated alternative to chemotherapy as a first-line, technorati.com
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