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We have 6 results for Helicase.
1 Citation PcrA helicase, a member of the superfamily 1, is an essential enzyme in many bacteria. The first crystal structures of helicases were obtained with PcrA. Based on structural and biochemical studies, it was proposed and then generally believed that PcrA is a monomeric helicase that unwinds DNA by an inchworm mechanism.It was found that the PcrA-catalysed DNA unwinding depended strongly on the PcrA concentration as well as on the 3?-ssDNA tail length of the substrate, indicating that an oligomeriz, technorati.com
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1 Citation November 27, 2008 at 3:19 pm (Bloom's syndrome) Tags: BLM, helicase Robert Brosh, Jr. wrote an article on Nature about the BLM helicase . His introductory paragraph goes: ?Bloom?s syndrome, which is characterized by severe growth retardation, immunodeficiency, anaemia, reduced fertility and predisposition to cancer1, is caused by mutations in the gene BLM. At the cellular level, technorati.com
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Molecular machine turns packaged messenger RNA into a linear transcript (PhysOrg) 1 Citation For RNA, the gateway to a productive life outside the nucleus is the nuclear pore complex, an amalgamation of 30 kinds of proteins that regulates all traffic passing through the nuclear membrane. New research from Rockefeller University shows that one of these proteins magnetically couples with a special molecule ? a helicase ? to form a machine that unpacks balled-up messenger RNA particles so ..., technorati.com
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A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs 1 Citation Link to original article : In humans a single species of the RNAseIII enzyme Dicer processes both microRNA precursors into miRNAs and long double-stranded RNAs into small interfering RNAs (siRNAs). An interesting but poorly understood domain of the mammalian Dicer protein is the N-terminal helicase-like domain that possesses a signature DExH motif. Cummins et al. created a human Dicer mutant cell line by inserting an AAV targeting cassette into the helicase domain of both Dicer alleles in H, technorati.com
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Molecular Machine Turns Packaged Messenger RNA Into A Linear Tra... 1 Citation For RNA, the gateway to a productive life outside the nucleus is the nuclear pore complex, an amalgamation of 30 kinds of proteins that regulates all traffic passing through the nuclear membrane. New research shows that one of these proteins magnetically couples with a special molecule -- a helicase -- to form a machine that unpacks balled-up messenger RNA particles so that they can be translated., technorati.com
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1 Citation The unwinding process of two strands of DNA is catalyzed by enzymes called DNA helicases. The major DNA helicase in E. coli to the product of the dnaB gene. The helicases unwind DNA molecules using energy derived from ATA., technorati.com
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