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1Choke on this: The hypoxia pathway extends lifespan and reduces proteotoxicity 1 Citation Protein degradation is an essential longevity assurance pathway. Maintaining high levels of autophagy can delay age-related decline in liver function . Obstacles to protein degradation tend to shorten the lifespan: blocking autophagy causes hypersensitivity to stress , and inhibiting the ubiquitin/proteasome pathway damages the mitochondria ; both of these treatments kill neurons. Conversely, longevity enhancement tends to enhance disposal of cellular garbage: In a worm model of Alzheim, technorati.com
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Which dental local anesthetic should be avoided with our elderly? 1 Citation Methemoglobinemia is a disorder characterized by the presence of a higher than normal level of methemoglobin in the blood. Methemoglobin is a form of hemoglobin that does not bind oxygen. When its concentration is elevated in red blood cells, anemia and tissue hypoxia can occur. Both 4% amides solutions articaine and prilocaine commonly used in dental procedures as a local anesthetic may produce methemoglobin especially in elderly and medically compromised patients but can be a problem i, technorati.com
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Let?s Roll Red Tides Out of the Ocean 1 Citation With apologies to the Alabama Crimson Tide, it?s time to ?Roll Red Tides, Roll!? right out of the ocean. Red Tides and other Harmful Algal Blooms (HABs) are occurring more and more frequently along all U.S. coasts, including the Great Lakes. They impose huge costs to coastal ecosystems, human health and regional economies. HABs are caused by many factors, including light, salinity, water temperature, and nutrient levels in the water. In some regions, the specific sources of the problem a, technorati.com
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Cambrian explosion and Ocean Chemistry 1 Citation About 530 million years ago the ocean chemistry changed dramatically with a jump in the concentration of sulphate in the oceans. This was more or less simultaneous with the seemingly rapid appearance of a wide variety of multiple-celled organisms, an event known as the Cambrian Explosion. The chicken or egg question is, whether one of these two events caused the other. According to a paper in the 18 May 2009 issue of the scientific journal Proceedings of the National Academy of Sciences ( PNAS, technorati.com
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NADPH Oxidase Adds to Obstructive Sleep Apnea Issues 1 Citation Obstructive Sleep Apnea has become a growing concern and while others try to look for a cure, some scientists continue to study and detect the cause by it. And apparently, there is one enzyme found to be the culprit of it all. The enzyme is known as the NADPH Oxidase. This was discovered by researchers from Emory University. Obstructive sleep apnea is stated to be a sleeping disorder which may be characterized by breaks or pauses in breathing during sleep. It has been estimated that 1 out of e, technorati.com
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what does Isherwood stand for? 1 Citation Isherwood stands for United States writer (born in England) whose best known novels portray Berlin in the 1930''s and who collaborated with W. H. Auden in writing plays in verse (1904-1986), technorati.com
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1 Citation Bubble Trouble : A review of diving physiology. Levitt, D & Millar, I. Post Graduate Med J. 2008; 84 :571-78. Arterial Blood Gas and oxygen content in climbers on Mount Everest. Grocott, M et al. NEJM. 2009. 360:2;140-49 Something a bit different from the usual critical appraisal. Two recent papers highlighting the potential of studying normal physiology , technorati.com
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1 Citation Lack of oxygen to the brain, which may occur during DROWNING, childbirth, or choking. Hypoxia during birth is one of the primary causes of CEREBRAL PALSY and may be related to LEARNING DISABILITIES., technorati.com
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Sprawling crocodylians walk straight even if there isn?t much O2 to go around. 1 Citation Photo of estuarine crocodile by: D. Parer and E. Parer-Cook Two new papers have recently hit the journal circuit. Both of them involve using living crocodylians to gain a better understanding of paleo-life. The first one comes from Denver Museum of Natural History paleontologist, Dr. Kenneth Carpenter: Carpenter, K. 2009. Role of Lateral Body Bending in Crocodylian Track Making. Ichnos. Vol.16:202-207. doi:10.1080/10420940802686137. The study used an adult Caiman sclerops (first use, technorati.com
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what does isinglass stand for? 1 Citation isinglass stands for any of various minerals consisting of hydrous silicates of aluminum or potassium etc. that crystallize in forms that allow perfect cleavage into very thin leaves, technorati.com
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