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1New nucleotide could revolutionize epigenetics 5 Citations It accounted for roughly 40 percent of the methylated cytosine in Purkinje cells and 10 percent in granule neurons. He then performed a series of tests on 'x,' including mass spectrometry, which determines the elemental components of molecules by breaking them down into their constituent parts, charging the particles and measuring their mass-to-charge ratio. He repeated the experiments more than 10 times and came up with the same result: x was 5-hydroxymethylcytosine, a stable nucleotide previously observed only in the simplest of life forms, bacterial viruses. A number of other tests showed that 'x' could not be a byproduct of age, DNA damage during the cell-type isolation procedure or RNA contamination. "It's stable and it's abundant in the mouse and human brain," Kriaucionis says. "It's really exciting.", delicious.com
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New Gene Switch Sows Epigenetic Doubts 1 Citation
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http://www.biomedcentral.com/content/pdf/1471-2164-8-293.pdf 1 Citation mtDNA control region mutations and leukocytes, delicious.com
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New Gene Switch Sows Epigenetic Doubts | Wired Science from Wired.com 1 Citation
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A, T, G, C and What? | Popular Science 1 Citation
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Nucleotide - Vibrio parahaemolyticus RIMD 2210633 chromosome II... 1 Citation
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New Nucleotide In DNA Could Revolutionize Epigenetics 1 Citation
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Chemist Shows How RNA Can Be the Starting Point for Life - NYTimes.com 1 Citation how the building blocks of RNA, called nucleotides, could have spontaneously assembled themselves in the conditions of the primitive earth. The discovery, if correct, should set researchers on the right track to solving many other mysteries about the origin of life., delicious.com
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