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1 | 2 | Next2 Citations Métodos, Mecanismos celulares que controlan la proliferación, ......, delicious.com
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1 Citation Mutation of proto-oncogenes may convert them to oncogenes , while mutation of tumor suppressor genes may cause a loss of anti - proliferative functions. Based on computational analysis of mutations affecting CAN-genes (candidate cancer genes) in breast and colorectal carcinomas, it has been estimated that cancers average 17 mutations (mostly SNPs ) occurring within at least 90 genes . Cancers originating in the same tissue display mutation of different genes, and mutated genes, technorati.com
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1 Citation Cancers arise when cells escape normal controls on cellular proliferation . Cancer is not a single disease, rather the term encompasses a group of conditions that share the characteristic process of uncontrolled proliferation of cells that are typically capable of local infiltration into other tissues (invasion). This propensity for invasion and migration is associated with the capacity of malignant tumors to metastasize to sites distant from the point of origin. This propensity for in, technorati.com
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1 Citation The proto-oncogene c-fos participates in cellular proliferation by encoding a transcription factor , fos that forms homodimers, or heterodimers with the proto-oncogene c-jun (as AP1 ). The human homolog of the fos oncogene has been mapped to chromosome region 14q21?q31, and is overexpressed in a variety of cancers . Retrovirus -associated v-fos DNA sequences were originally isolated from murine sarcoma viruses, and fos is named for feline osteosarcoma virus. AP1 : AP1 re, technorati.com
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Scientists move a step closer to creating ideal neural cells for clinical use 1 Citation Washington, April 14 (ANI): Scientists at the Burnham Institute for Medical Research (Burnham) have come up with a way to convert human embryonic stem cells (hESCs) into neural progenitor cells, which may be ideal for transplantation. Lead researcher Dr. Alexei Terskikh says that the new method to create these committed neural precursor cells (C-NPCs) does not , technorati.com
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How does cancer spread and how deadly is it? 1 Citation Every century brings with it a disease, which is perceived as incurable and later on a cure is established and in many cases the disease completely eradicated. But what can one do if the disease is caused not by external factors but from within? Cancer is not caused due to viruses, bacteria or protozoa, instead it is caused by cells in the human body which lose control of themselves. These cells are called proto-oncogenes, once they get activated, for whatever reason, they are called oncogenes., technorati.com
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1 Citation Alteration of a gene that normally controls cell growth can promote the uncontrolled growth characteristic of cancer. The normal form of the gene is termed a proto-oncogene , and the malignantly transformed gene is termed an oncogene . Oncogenes : c-Fos : c-Jun : c-Myc : c-Sis : Ras : Rb : Tumor Suppressor Genes : TP53 Damaged genes are passed down through the cancer cell line, and may be dominant or recessive genes: Recessive : tumor suppressors , growth supp, technorati.com
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1 Citation
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1 Citation Mutation of proto-oncogenes may convert them to oncogenes , while mutation of tumor suppressor genes may cause a loss of anti - proliferative functions. Based on computational analysis of mutations affecting CAN-genes (candidate cancer genes) in breast and colorectal carcinomas, it has been estimated that cancers average 17 mutations (mostly SNPs ) occurring within at least 90 genes . Cancers originating in the same tissue display mutation of different genes, and mutated genes, technorati.com
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Module Map Links Embryonic Stem Cells And Cancer Stem Cells 1 Citation Module Map Links Embryonic Stem Cells And Cancer Stem Cells Friday, November 14, 2008 8:52 "Self-renewal is a hallmark of stem cells and cancer, but existence of a shared stemness program remains controversial," explains study co-author, Dr. Howard Y. Chang from Stanford University. Dr. Chang, Dr. Eran Segal from the Weizmann Institute in Israel and their colleagues constructed a gene module map to systematically relate transcriptional programs in embryonic stem cells (ESCs), adult tissue stem, technorati.com
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