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1Patients, Physicians Invited to Lupus Education Day 1 Citation Lupus :: Patients, Physicians Invited to Lupus Education Day Patients and physicians are invited to a Lupus Education Day to learn more about an oft-misunderstood disease, but one for which several potential new treatments are in development. Doctors and nurses from the lupus clinic at Strong Memorial Hospital will spend Saturday, Oct. 13, offering an educational program at the University of Rochester Medical Center. The afternoon session, geared to patients and family members, is free of ch, technorati.com
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Sperm abnormalities seen in male lupus patients 1 Citation Sperm :: Sperm abnormalities seen in male lupus patients The prognosis for systemic lupus erythematosus (SLE), an autoimmune disease that mainly affects women in their reproductive years, has improved recently, prompting a shift toward improving quality of life. For men with SLE, concerns have been raised about their future fertility. However, no studies have been conducted to date on testes function and its relevance to sperm abnormalities in male SLE patients. A new study published in th, technorati.com
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Interferon-regulated chemokines and SLE 1 Citation Systemic Lupus Erythematosus :: Interferon-regulated chemokines and SLE A comprehensive survey of the serologic proteome in human SLE suggests that severely disrupted chemokine gradients may contribute to the systemic autoimmunity observed. Systemic lupus erythematosus (SLE or lupus) is a chronic autoimmune disease that is potentially debilitating and sometimes fatal as the immune system attacks the body?s cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part, technorati.com
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Involvement of the amygdala in systemic lupus erythematosus 1 Citation Systemic Lupus Erythematosus :: Involvement of the amygdala in systemic lupus erythematosus In a mouse model of systemic lupus erythematosus (SLE), anti-NMDA receptor antibodies have been shown to gain access to the brain during stress, specifically damaging the amygdala (a part of the brain that is involved in emotion) and causing altered emotional responses. In a paper published in PLoS Medicine from Leiden University Medical Center of 37 patients with neuropsychiatric SLE, 21 patients wit, technorati.com
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Over one-third of refractory lupus patients remain stable at long term follow-up 1 Citation Lupus :: Over one-third of refractory lupus patients remain stable at long term follow-up Thirty-six percent of patients with refractory systemic lupus erythematosus remain well after undergoing B-cell depletion therapy without needing further standard immunosuppressive agents, according to a study presented today at EULAR 2007, the Annual European Congress of Rheumatology in Barcelona, Spain. Overactive B-cells are commonly found in patients with SLE and reducing the number of B-cells in th, technorati.com
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Older, lower income patients least likely to see a specialist for lupus 1 Citation Lupus :: Older, lower income patients least likely to see a specialist for lupus Despite advances in treatment, systemic lupus erythematosus (SLE) remains a serious disease. Previous studies have shown that racial and ethnic minorities and individuals with low socioeconomic status may have poorer outcomes in the long run. Other research has shown that care provided by specialists to patients with rheumatic diseases is associated with improved outcomes yet does not cost more. A new study publ, technorati.com
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Existing drugs show promise for treating end-stage renal disease in lupus 1 Citation Lupus :: Existing drugs show promise for treating end-stage renal disease in lupus Studies in mice suggest that two drugs already approved by the U.S. Food and Drug Administration show promise for treating the complications of lupus, according to Nilamadham Mishra, M.D., in presentations this week at the American College of Rheumatology in Boston. Mishra, a rheumatologist at Wake Forest University Baptist Medical Center, had previously reported that an anti-seizure medication and a chemother, technorati.com
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Immunosuppressive drug effective for reducing lupus flares 1 Citation Lupus :: Immunosuppressive drug effective for reducing lupus flares Mayo Clinic researchers have shown that an immunosuppressive drug used in organ transplant cases is effective in reducing flare-ups in patients with systemic lupus erythematosus (SLE). SLE results in inflammation of connective tissues and can involve the skin, joints and kidneys. Its cause is unknown. The findings were announced today at the annual meeting of the American College of Rheumatology in Boston. ?Our findings show, technorati.com
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Mirac stops the proliferation of cells that cause Lupus 1 Citation Lupus :: Mirac stops the proliferation of cells that cause Lupus Lupus is caused by Natural Killer (NK) CD4? and CD8? T-Lymphocytes, also called T cells. These T cells multiply using a potassium gene channel. These same cells cause Diabetes. (Eur J Immunol. 1990 Apr;20(4):747-51. Autoimmune diseases linked to abnormal K+ channel expression in double-negative CD4-CD8- T cells. Chandy KG, Cahalan MD, Grissmer S. Department of Medicine, University of California, Irvine) By blocking this gene, technorati.com
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Safety concern regarding Rituxan in systemic lupus erythematosus 1 Citation Systemic Lupus Erythematosus :: Safety concern regarding Rituxan in systemic lupus erythematosus The Food and Drug Administration (FDA) is alerting health care professionals and patients treated with Rituxan (rituximab) to reports of an emerging risk of a serious side effect in patients receiving or who have used Rituxan. FDA recently learned that two patients who were treated with Rituxan for systemic lupus erythematosus (SLE) developed progressive multifocal leukoencephalopathy (PML), a fa, technorati.com
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